What/how/why, etc. in the world:Used to emphasize your surprise when asking a question.

Usage:
What in the world are you doing in the cupboard?

Excerpts from soaps, novels and films:

Bold and the beautiful

“Nick: I need to ask you something. Do you think the old man had anything to do with you being arrested?

Massimo: What in the world is the matter with you? Coming to see me while ridge is here?”

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